Preimplantation genetic screening (PGS) is a technique in which embryo biopsy is used to evaluate the genetic material of the embryo created through invitro fertilization (IVF). This particular genetic analysis is performed to look for an abnormal number of chromosomes (aneuploidy) or for a chromosomal translocation, both of which may cause miscarriages. A normal embryo must have 46 chromosomes in the right combination to enable normal viability- 23 from the mother and 23 from the father.
Chromosomal abnormalities can result in aneuploidy (embryo having the wrong number of chromosomes- i.e extra copy of chromoseome 21 also known as Downs Syndrome), translocations (chromosomes incorrectly rearranged), or other chromosome alterations that may be clinically significant PGS aims at improving pregnancy and live birth rates by screening your embryos for chromosomal abnormalities. Embryos free of aneuploidy can be selected&transferred back to the patient